Ponca Tribe of Nebraska
125 6th Street, Sioux City, IA 51103

Looking for medication-assisted treatment (mat) in Sioux City? 7 of the city's 27 listed providers offer it.
Medication-assisted treatment pairs counseling with FDA-approved medication: buprenorphine (Suboxone and similar), naltrexone (Vivitrol) or methadone for opioid use disorder, and naltrexone or acamprosate for alcohol use disorder. MAT lowers the risk of overdose death.
125 6th Street, Sioux City, IA 51103
3200 West 4th Street, Sioux City, IA 51103
1419 Casselman Street, Sioux City, IA 51103
1800 Grandview Boulevard, Sioux City, IA 51105
800 5th Street, Sioux City, IA 51101
3500 W. 4th St., Sioux City, IA 51103
800 5th Street, Sioux City, IA 51101
We list 7 facilities in Sioux City, IA reporting mat services. Call ahead to confirm availability and wait times.
Ask each facility whether they are licensed by Iowa, whether they accept your insurance or Medicaid, how soon they can admit you, and whether they offer medication for opioid or alcohol use disorder.
Last reviewed 2026-10-06. Facility details come from SAMHSA's FindTreatment.gov locator and facility-provided information. Confirm services, availability and payment directly with the facility.